Research Database

8 results for "Alzheimer disease"

Is Cognitive Training More Effective When Conducted After Physical Exercise?

  • Published on March 10, 2019

Acute increases in brain-derived neurotrophic factor in plasma following physical exercise relates to subsequent learning in older adults Gradual decline of certain cognitive abilities, including conceptual reasoning, memory, and processing speed, is a normal part of the aging process. Brain-derived neurotrophic factor (BDNF) is a protein that plays an essential ...

Moderate intensity physical activity associates with CSF biomarkers in a cohort at risk for Alzheimer’s disease

  • Published on Feb 6, 2018

Introduction: Alzheimer's disease (AD) is characterized by the presence of amyloid β (Aβ) plaques, neurofibrillary tangles, and neurodegeneration, evidence of which may be detected in vivo via cerebrospinal fluid (CSF) sampling. Physical activity (PA) has emerged as a possible modifier of these AD-related pathological changes. Consequently, the aim of this study ...

Moderate Physical Activity is Associated with Cerebral Glucose Metabolism in Adults at Risk for Alzheimer’s Disease

  • Published on Jun 23, 2017

The objective of this study was to investigate the relationship between accelerometer-measured physical activity (PA) and glucose metabolism in asymptomatic late-middle-aged adults. Ninety-three cognitively healthy late-middle-aged adults from the Wisconsin Registry for Alzheimer’s Prevention participated in this cross-sectional study. They underwent 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) imaging and wore ...

Intra-Individual Variability of Physical Activity in Older Adults With and Without Mild Alzheimer’s Disease

  • Published on Apr 20, 2016

Abstract: Physical activity shows promise for protection against cognitive decline in older adults with and without Alzheimer's disease (AD). To better understand barriers to adoption of physical activity in this population, a clear understanding of daily and weekly activity patterns is needed. Most accelerometry studies report average physical activity over ...

Intense physical activity is associated with cognitive performance in the elderly

  • Published on Nov. 20, 2012

Numerous studies have reported positive impacts of physical activity on cognitive function. However, the majority of these studies have utilised physical activity questionnaires or surveys, thus results may have been influenced by reporting biases. Through the objective measurement of routine levels of physical activity via actigraphy, we report a significant ...