Research Study Abstract

Mobility disability and the pattern of accelerometer-derived sedentary and physical activity behaviors in people with multiple sclerosis

  • Published on Apr 1, 2016

Objective: Low physical activity and high sedentary behavior levels are major concerns in persons with multiple sclerosis (MS) and these differ depending on the level of mobility disability. However, the manner in which daily activity is accumulated is currently unknown in this population.

Methods: A secondary analysis was performed on a combined data set of persons with MS from two previous investigations of physical activity and symptomatic or quality of life outcomes in the United States over a two year period (2007-2009). Mobility disability status was determined using the Patient Determined Disease Steps (PDDS) while activity behavior was objectively monitored using an ActiGraph accelerometer for 7 days.

Results: Persons with MS who have mobility disability were involved in sedentary behavior, light and moderate intensity activity for 65%, 34% and 1% of the day, respectively compared to 60%, 37%, and 3%, respectively in those without mobility disability (p < 0.05). Breaks in sedentary time did not differ by mobility disability status. Compared to those without mobility disability, the average number of sedentary bouts longer than 30 min was greater in those with mobility disability (p = 0.016).

Conclusion: Persons with MS with mobility disability are less active, engage in more sedentary behavior and accumulate prolonged sedentary bouts.


  • Ezeugwu V 1
  • Klaren RE 2
  • A Hubbard E 2
  • Manns PT 1
  • Motl RW 2


  • 1

    Department of Physical Therapy, University of Alberta, Edmonton, Canada.

  • 2

    Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, USA.


PubMed - Preventive Medicine Reports


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